{"id":896,"date":"2023-05-11T10:03:57","date_gmt":"2023-05-11T10:03:57","guid":{"rendered":"https:\/\/cbit.webs.upv.es\/?page_id=896"},"modified":"2023-05-11T10:23:22","modified_gmt":"2023-05-11T10:23:22","slug":"inocoes-cat","status":"publish","type":"page","link":"https:\/\/cbit.webs.upv.es\/index.php\/showcase\/inocoes-cat\/","title":{"rendered":"INOCOES-CAT"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2-1024x896.png\" alt=\"\" class=\"wp-image-898\" width=\"183\" height=\"160\" srcset=\"https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2-1024x896.png 1024w, https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2-300x263.png 300w, https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2-768x672.png 768w, https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2.png 1236w\" sizes=\"auto, (max-width: 183px) 100vw, 183px\" \/><\/figure>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\">Ocular insert manufactured by multi-jet coaxial electrospinning for the postoperative treatment of cataracts.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In this project, we propose to develop a system for the <strong>controlled release of three biomolecules<\/strong> in the eye for the postoperative treatment of <strong>cataract surgery<\/strong>. Each drug will be released with a different time-dependent profile, according to the needs of the treatment (see Figure 1). We will manufacture prototypes according to clinical requirements and we will carry out their evaluation in preclinical phases. The system is based on an <strong>ocular insert<\/strong> design for placement in the conjunctival sac. This ocular insert will be constructed \u00a0\u00a0using the <strong>multi-jet coaxial electrospinning<\/strong> technique, which allows the manufacture of membranes made up of very fine fibres, with a core\/shell structure that allows to encapsulate the drugs inside the fibre. The release of the drugs will be regulated using biodegradable polymers in the shell part of the fibres, with a rate of release of the drugs dependent on the polymer rate of degradation.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"881\" height=\"352\" src=\"https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-1.png\" alt=\"\" class=\"wp-image-897\" srcset=\"https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-1.png 881w, https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-1-300x120.png 300w, https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-1-768x307.png 768w\" sizes=\"auto, (max-width: 881px) 100vw, 881px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Ocular insert manufactured by multi-jet coaxial electrospinning for the postoperative treatment of cataracts. In this project, we propose to develop&hellip;<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":343,"menu_order":1,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-896","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>INOCOES-CAT - CBIT<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cbit.webs.upv.es\/index.php\/showcase\/inocoes-cat\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"INOCOES-CAT - CBIT\" \/>\n<meta property=\"og:description\" content=\"Ocular insert manufactured by multi-jet coaxial electrospinning for the postoperative treatment of cataracts. In this project, we propose to develop&hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/cbit.webs.upv.es\/index.php\/showcase\/inocoes-cat\/\" \/>\n<meta property=\"og:site_name\" content=\"CBIT\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-11T10:23:22+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cbit.webs.upv.es\/wp-content\/uploads\/2023\/05\/image-2-1024x896.png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@CBIT_upv\" \/>\n<meta name=\"twitter:label1\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutos\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/\",\"url\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/\",\"name\":\"INOCOES-CAT - CBIT\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cbit.webs.upv.es\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/image-2-1024x896.png\",\"datePublished\":\"2023-05-11T10:03:57+00:00\",\"dateModified\":\"2023-05-11T10:23:22+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/#breadcrumb\"},\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/#primaryimage\",\"url\":\"https:\\\/\\\/cbit.webs.upv.es\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/image-2.png\",\"contentUrl\":\"https:\\\/\\\/cbit.webs.upv.es\\\/wp-content\\\/uploads\\\/2023\\\/05\\\/image-2.png\",\"width\":1236,\"height\":1082},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/inocoes-cat\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/cbit.webs.upv.es\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Projects Showcase\",\"item\":\"https:\\\/\\\/cbit.webs.upv.es\\\/index.php\\\/showcase\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"INOCOES-CAT\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#website\",\"url\":\"https:\\\/\\\/cbit.webs.upv.es\\\/\",\"name\":\"Centre for Biomaterials and Tissue Engineering - UPV\",\"description\":\"Centre for Biomaterials and Tissue Engineering at the Universitat Polit\u00e8cnica de Val\u00e8ncia\",\"publisher\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/cbit.webs.upv.es\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"es\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#organization\",\"name\":\"Centre for Biomaterials and Tissue Engineering - UPV\",\"url\":\"https:\\\/\\\/cbit.webs.upv.es\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"es\",\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/cbit.webs.upv.es\\\/wp-content\\\/uploads\\\/2019\\\/10\\\/logo-CBIT-grande.png\",\"contentUrl\":\"https:\\\/\\\/cbit.webs.upv.es\\\/wp-content\\\/uploads\\\/2019\\\/10\\\/logo-CBIT-grande.png\",\"width\":2268,\"height\":689,\"caption\":\"Centre for Biomaterials and Tissue Engineering - UPV\"},\"image\":{\"@id\":\"https:\\\/\\\/cbit.webs.upv.es\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/x.com\\\/CBIT_upv\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"INOCOES-CAT - CBIT","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/cbit.webs.upv.es\/index.php\/showcase\/inocoes-cat\/","og_locale":"es_ES","og_type":"article","og_title":"INOCOES-CAT - CBIT","og_description":"Ocular insert manufactured by multi-jet coaxial electrospinning for the postoperative treatment of cataracts. 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